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Front Endocrinol (Lausanne) 12
Hair loss is emerging as a possible side effect of GLP-1 drugs
In the PIONEER-6 trial funded by Novo Nordisk the manufacturer of Wegovy and Ozempic oral semaglutide performed better than a placebo, particularly at high weekly doses of 14 milligrams (mg) that produced a 21% reduction in cardiovascular risk
The intensity of these adverse effects is typically dose-related, with higher dosages associated with more severe symptoms
Constipation may increase initially because both reduced food volume and slower gastric transit contribute to this issue
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